CAR T-Cell Therapy
Graphical Abstract
Scroll down to learn more about our work in visualizing cancer cell therapy.
Client: Quanterix
Quanterix approached us to create an infographic for their White Paper document that details their Simoa® assay’s ability to detect low levels of cytokines during CAR T-cell therapy. Their Simoa® platform can monitor CRS in addition to neurotoxicity with the goal of successful and safe cell therapy.
01 - Overview
Artists:
Tiffany Fung
Margot Ceelen
CAR T-Cell Therapy and Simoa early detection technology
02 - What is CAR T-Cell Therapy?
CAR T-cell therapy is an immunotherapy treatment against cancer. T cells are a part of the immune system that are in charge of attacking foreign particles, such as cancer cells. However, cancer can often hide from its attackers. CAR T-cells are specially engineered lymphocytes that can recognize the particular antigen of the specific cancer and be used in immunotherapy. When immune cells are activated during the destruction of cancer cells, the body is flooded with a large amount of cytokines which can lead to cytokine release syndrome (CRS). These include life threatening symptoms such as hypertension, capillary leak, and cardiac dysfunction to name a few.
03 - Our Solution ✨
We designed this graphical abstract to detail the process of CAR T-cell therapy - from CAR T-cell creation to infusion to cancer apoptosis to adverse affects to the immunotherapy. Combining such a large quantity of information proved challenging. In order to clearly communicate this process, we utilized 3 column approach. This separates external processes from internal ones by using the blood vessel as a literal and symbolic barrier. When creating a complex graphic like this one, it is important to be strategic with the amount of colors used.
Let’s Chat
Do you need an infographic or graphical abstract to visualize the mechanisms of action of your cell therapy? Reach out to us and we can start the conversation.